comparing the effect of visceral fat and barley seed ash (hordeum vulgare l) with silversulfadiazine on burn wound healing in rats

نویسندگان

mohammad azadi gerash research center, shiraz university of medical sciences, shiraz, ir iran

hossein foruozandeh toxicology research center, department of pharmacology and toxicology, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; corresponding author: hossein foruozandeh, department of pharmacology and toxicology, toxicology research center, ahvaz jundishapur university of medical science, ahvaz, ir iran. tel: +98-9379873029

leila karami amiralmomenin hospital, shiraz university of medical sciences, grash, ir iran

mohammad javad khodayar toxicology research center, department of pharmacology and toxicology, ahvaz jundishapur university of medical sciences, ahvaz, ir iran

چکیده

conclusions traditional preparation significantly decreased inflammation and accelerated wound healing in treated rats. furthermore, the findings of this study can be applied clinically in the future. background skin burn is one of the most common complications and remains a major public health issue worldwide. objectives this experiment was conducted to study the effects of traditional medicine (visceral fat and barely seed ash) compared with silversulfadiazine (ssd) cream on healing burn wounds in rats. results ssd cream and traditional preparation had better effects on burnt wound healing compared with control group. furthermore, on the final day of study, the average percentage of wound concentration in traditional medicine group was significantly greater than other groups (p < 0.05). this finding was supported and confirmed by histological examination as well. materials and methods sixty adult male wistar rats were randomly divided into four groups of equal numbers; each group consisted of 15 animals. after sedation, type ii of skin burn with 1.5 cm diameter circle was created on the back of rats with a heated metal in boiling water. group one was not treated and considered as control. the burned areas in the second, third and fourth groups were applied twice a day with normal saline, ssd cream and traditional preparation, respectively. percentage of the burn wound concentration and histopathological examinations were used as parameters of our study on days 4, 9and 14. obtained data were compared between the groups and days.

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Comparing the Effect of Visceral Fat and Barley Seed Ash (Hordeum Vulgare L) With Silversulfadiazine on Burn Wound Healing in Rats

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عنوان ژورنال:
jundishapur journal of natural pharmaceutical products

جلد ۱۰، شماره ۱، صفحات ۰-۰

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